selected publications

books

1.     gabriel d. dakubo (editor). field cancerization: basic science and clinical applications.nova science publishers, inc. new york, usa (dec 2010):https://www.novapublishers.com/catalog/product_info.php?products_id=16705

2.     gabriel d. dakubo (author). mitochondrial genetics and cancer, doi 10.1007/978-3-642-11416-8_2, # springer-verlag berlin heidelberg 2010: http://www.springer.com/978-3- 642-11415-1

book chapters

1.     gabriel d. dakubo. introduction. in: field cancerization: basic science and clinical applications. gabriel d. dakubo (eds), nova science publishers, inc. new york, usa (dec 2010)

2.     gabriel d. dakubo. mitochondrial reactive oxygen species and cancer. chapter 3. in:handbook of free radicals: formation, types and effects (cell biology research progress). dimitri kozyrev and vasily slutsky (eds). nova science publishers, inc. new york, usa (2010)

3.     gabriel d dakubo, ryan l. parr, and john p. jakupciak. prostate cancer: detection and monitoring using mitochondrial mutations as a biomarker. chapter 32. in: methods of cancer diagnosis, therapy and prognosis. general methods and overviews, lung carcinoma and prostate carcinoma (vol. 2) hayat, m.a. (ed). springer. usa (2009).chapter 32, pg. 441-464.

peer-review publications

 
mitochondrial genomics and cancer

 

1.      robinson k, creed j, reguly b, powell c, wittock r, klein d, maggrah a, klotz l, parr rl,dakubo gd. accurate prediction of repeat prostate biopsy outcomes by a mitochondrial dna deletion assay. prostate cancer and prostatic diseases, 2010, 13(2); 126-131.

 

2.     jakupciak jp, maggrah a, maragh s, maki j, reguly b, maki k, wittock r, robinson k, wagner pd, thayer re, gehman k, gehman t, srivastava s, and dakubo gd, parr lp. facile whole mitochondrial genome resequencing from nipple aspirate fluid using mitochip v2.0. bmc cancer 2008; 8:95

 

3.     dakubo gd, mitochondrial genome analysis in biofluids for early cancer detection and monitoring. expert opinion on medical diagnostics. 2008; 2:263-275

 

4.     maki j, robinson k, reguly b, alexander j, wittock r, aguirre a, diamandis ep, escott n, skehan a, prowse o, thayer er, m. froberg k, wilson mj, maragh s, jakupciak jp, wagner pd, srivatava s, dakubo gd, parr rl. mitochondrial genome deletion aids in the identification of both false and true negative prostate needle core biopsies. american journal of clinical pathology. 2008; 129:57-66

 

5.     parr rl, jakupciak jp, birch-machin ma, dakubo gd. the mitochondrial genome: a biosensor for early cancer detection? expert opinion on medical diagnostics. 2007; 1: 169-182

 

6.     dakubo gd, jakupciak, jp, birch-machin ma, and parr, lr. clinical implication and utility of field cancerization. cancer cell international. 2007; 7:2

 

7.     jakupciak, jp, dakubo,gd, maragh, s, and parr, lr. mitochondrial dna as a cancer biomarker. current opinion in molecular therapeutics.  2006; 8:500-506

 

8.     parr, r., maki, j., reguly, b., dakubo, gd., aguirre, a., wittock, r. and robinson, k., thayer, r., the pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation.  bmc genomics, 2006; 7:185

 

9.     parr, r., dakubo, gd., maki, j., reguly, b., wittock, r., robinson, k., alexander, j., birch-machin, m., abdel-malak, m., froberg, k., diamamdis, e. and thayer, r.e., high somatic mitochondrial dna mutations in prostate cancer and normal appearing in adjacent glands in comparison to age-matched prostate sample without malignant histology. journal of molecular diagnostics. 2006; 8:312-19

 

10. parr, r. dakubo, gd., thayer, r., mckenney, k. and birch-machin, m., mitochondrial dna as a potential tool for early cancer detection. human genomics. 2006; 2:252-257

 

11. dakubo, gd., parr, r., costello, l.c., franklin, r.b., and thayer, r.e., altered metabolism and mitochondrial genome in prostate cancer. journal of clinical pathology. 2006; 59:10-16

developmental biology

 

1.      dakubo gd, beug s, mazerolle c, thurig s, wang, y, wallace  va. control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells. brain research 2008; 1228:27-42

 

2.      dakubo gd, furimsky m, mazerolle c, yu c, st-jacques b, mcmahon ap, and wallace va. ihh signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye. developmental biology 2008; 320:242-255  

 

3.      karamboulas, c., dakubo, gd., liu, j., de repentigny, y., yutzey, k., wallace, v., kothary, r., and skerjanc, i., disruption of mef2 activity in cardiomyoblasts inhibits cardiomyogenesis.  journal of cell science. 2006; 119:4315-4321.

 

4.      dakubo, gd., mazerolle, c., and wallace, v.  expression of notch and wnt pathway components and activation of notch signaling in medulloblastomas from heterozygouspatched mice. journal of neuro-oncology, 2006; 79:221-227

 

5.     wang, yp, dakubo, gd., thurig, s., mazerolle, c., and wallace, a.  retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of rgc development in the embryonic mouse retina. development 2005; 132:5103-5113

 

6.      dakubo, gd. and wallace, v., hedgehogs and retinal ganglion cells: organizers of the mammalian retina. neuroreport 2004; 15:476-482

 

7.      dakubo, gd., wang, y., mazerolle, c., campsall, k., mcmahon, a. and wallace, v.  retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. development 2003; 130:2967-2980

 

8.      wang, y., dakubo, g., howley, p., campsall, k., mazerolle, c., shiga, s., lewis, p., mcmahon, a. and wallace, v. development of normal retinal organization depends on sonic hedgehog signalling from ganglion cells. nature neuroscience 2002; 5:831-832