defense health program department of defense peer reviewed orthopaedic research program funding opportunities for fiscal year 2019 (fy19)
the fiscal year 2019 (fy19) defense appropriation provides $30 million (m) to the department of defense peer reviewed orthopaedic research program (prorp) to support the most significant gaps in care for the leading burden of injury and for facilitating return to duty by funding innovative, high-impact, clinically relevant research to advance optimal treatment and rehabilitation from musculoskeletal injuries sustained during combat and combat-related activities. the managing agent for the anticipated program announcements/funding opportunities is the congressionally directed medical research programs (cdmrp) at the u.s. army medical research and materiel command (usamrmc).
fy19 prorp program announcements and general application instructions for the following award mechanisms are posted on the grants.gov.
the prorp will solicit research applications that specifically address at least one of the following fy19 focus areas:
- 1. compartment syndrome models: diagnostic and/or treatment strategies developed in a large animal model that replicates compartment syndrome. model system should be clinically relevant and scientifically reproducible.
- 2. limb stabilization and protection: development of rapid limb stabilization and novel wound protectants for severely wounded limbs to enable transport at the point of need.
- 3. retention on duty strategies: development and/or optimization of battlefield-feasible diagnostic capabilities, decision support tools, interventions, and/or rehabilitation strategies that can facilitate retention on duty for common combat-related musculoskeletal injuries. (biomarker studies are excluded.)
- 4. skin-implant interface: identification of best practices to address infection at the skin-implant interface for osseointegrated prosthetic limbs.
- 5. translation of early findings: translation of early research findings in orthopaedic surgical care topic areas (volumetric muscle loss, compartment syndrome, and soft tissue trauma) to move the research toward clinical trials and clinical practice.
- 6. tissue regeneration therapeutics: development of advanced tissue regeneration therapeutics in nerve, muscle, and/or composite tissue for the restoration of traumatically injured extremities (excludes isolated bone tissue engineering studies).
the following fy19 prorp award mechanisms are planned for release (note that focus area requirements vary by award mechanism):
https://cdmrp.army.mil/funding/prorp
applied research award- preproposal is due june 26, 2019
independent investigators at all academic levels (or equivalent)
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clinical trial award – preproposal due june 26, 2029
independent investigators at all academic levels (or equivalent)
pre-application is required; full application submission is by invitation only.
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clinical translational research award – preproposal due june 26, 2019
independent investigators at all academic levels (or equivalent)
pre-application is required; full application submission is by invitation only.
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a pre-application is required and must be submitted through the electronic biomedical research application portal (ebrap) at https://ebrap.org prior to the pre-application deadline. all applications must conform to the final program announcements and general application instructions available for electronic downloading from the grants.gov website. the application package containing the required forms for each award mechanism will also be found on grants.gov. a listing of all cdmrp and other usamrmc extramural funding opportunities can be obtained on the grants.gov website by performing a basic search using cfda number 12.420.
for email notification when program announcements are released, subscribe to program-specific news and updates under “email subscriptions” on the ebrap homepage at https://ebrap.org. for more information about the prorp or other cdmrp-administered programs, please visit the cdmrp website(https://cdmrp.army.mil).
point of contact:
cdmrp help desk
301-682-5507
help@ebrap.org